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Nat Gantz I et al (1993) Molecular cloning, expression, and gene localization of a fourth melanocortin receptor

To conclude, although the use of model cell lines is now being superseded by more sophisticated models such as ex vivo cell cultures and organoids, model cell lines remain a low cost and fast alternative to screen the impact of drugs on a wide range of endocrine cells under buffer conditions that may not be well tolerated by ex vivo models and organoids

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The Dose-Response Relationship Recent case reports have highlighted a clear temporal and dose-response relationship between semaglutide and allodynia