Semaglutide alone markedly suppressed daily food intake post-initiation, with significantly reduced cumulative intake over 3 weeks versus Vehicle
The data suggests that while staying on the full dose of medication is the most effective way to prevent regain, it is not the only path forward
Effects of semaglutide treatment on inflammation factor in T2DM mice Fig 6 shows the serum levels of major inflammatory markers, including IL-1, IL-6, TNF-, and CRP, across the control, T2DM, semaglutide-treated, and dapagliflozin-treated groups
To finish up the side effects, the discontinuation rate excluding the weight loss stoppages appears at least a bit more reasonable as in most obesity trials the stop rate is usually 5-8% which only leaves the 12mg as an outlier still, but like I said earlier, we need side effects over time and just more data in general to see whats going on with that dose