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Mitochondria are the major source of reactive oxygen species (ROS) in cells

Activation of ferroptosis by IL-6 is may provide a new strategy for the treatment of advanced RCC and new ideas for TKIs resistance (146)

Since the serum Glu level is reportedly increased even in drug-nave patients [46], the effect of medication on the Glu level might be negligible

Patients should consult their healthcare provider before adding berberine to their regimen and implement more frequent blood glucose monitoring if using both therapies