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Statements Author contributions JW: Writingreview and editing, Conceptualization, Data curation, Investigation, Validation, Writingoriginal draft

Laboratory studies demonstrate that elimination of senescent cells through FOXO4-DRI administration can break the cycle of senescence induction and chronic inflammation, offering insights into interventions for age-related cellular dysfunction and tissue deterioration

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Benefits of B12 include increased energy, improved sleep and memory, decreased fatigue and increased metabolism