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Both tirzepatide and semaglutide mimic the hormone GLP-1, but tirzepatide also mimics another hormone, glucose-dependent insulinotropic polypeptide (GIP), and this may further contribute to weight loss

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Common pairings include M51.16 (lumbar disc degeneration), M47.816 (lumbar spondylosis with radiculopathy), M54.41/M54.42 (lumbago with sciatica, right or left side), and related lumbar radiculopathy codes

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