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Disclosures: Neuen reports receiving fees for travel support, advisory boards, scientific presentations and steering committee roles from Alexion, AstraZeneca, Bayer, Boehringer Ingelheim, Cambridge Healthcare Research, Cornerstone Medical Education, Janssen, the limbic, Medscape, Novo Nordisk and Travere Therapeutics, with all honoraria paid to The George Institute for Global Health

Here, we report the cryo-electron microscopy (cryo-EM) structures of GLP-1(9-36)-bound GLP-1R in complex with G s alone and in the presence of LSN3318839, with global resolutions of 3.0 and 3.2 , respectively ( Figs

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