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The Relationship Between Gastric Emptying and NSAIDs The most significant consideration when combining these two medications is the timing and duration of exposure in the stomach

J Clin Endocrinol Metab 103:30283037

Because these compounds are not FDA-approved, no approved prescribing information, drug interaction database, or dosing standard exists to guide clinicians, making physician oversight particularly important

There is large inter-person variability in response to GLP1 medications both in terms of weight loss and side effects, with the two potentially being related (that is, people who experience more nausea may lose more weight 30 )