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It is found that the cognitive impairment caused by transplanting feces from elderly people and aged mice into young mice is significantly more severe than feces from young adults and mice (Lee et al., 2020)
Extensive investigations of G6PD from G6PD-deficient cells, mostly carried out before the sequence of G6PD was known, revealed that (1) enzyme activity, even when severely reduced (sometimes to less than 1% of normal), is never completely absent and (2) enzymic properties ( K m , K i , activity on substrate analogues, and thermostability, for example) are often different from those of the normal enzyme (i.e., G6PD deficiency is associated with qualitative abnormalities)
Social isolation is associated with increased mortality, disability, and dementia
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