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Orexin receptor antagonists, a genuinely different approach to treating certain sleep disorders, work by blocking wakefulness-promoting signals rather than sedating the brain, and may eventually offer an option for patients whose insomnia doesnt respond to standard approaches
Less pull from the dopamine circuits
Amador, San Sebastin University, Chile Reviewed by Theodoros Androutsakos, National and Kapodistrian University of Athens, Greece Mehul Kaliya, All India Institute of Medical Sciences, India Updates Copyright 2026 Zhu, Wang, Zhang, Yang, Zhao, Li, Shi, Zhao and Ma
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