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Although long-acting DA and SS analogs are currently used in the treatment of prolactin (PRL)- and growth hormone (GH)-secreting pituitary tumors, respectively, clinical practice indicates a great variability in the frequency and entity of favorable responses

Incidence varies by dose and individual factors

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7.2 Complex cellular infiltration and angiogenesis Tophi, the defining pathological structures of chronic gout, arise through the coordinated actions of complex immune cell infiltration, persistent inflammation, and pathological angiogenesis rather than MSU crystal deposition alone