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Preventative strategies are particularly important for individuals experiencing recurrent outbreaks: Identify and minimise personal triggers (stress management, adequate sleep, sun protection) Consider suppressive antiviral therapy if outbreaks occur frequently (6 per year), as per NICE Clinical Knowledge Summary guidance Maintain optimal overall health, including good glycaemic control if diabetic Stay well-hydrated and manage any gastrointestinal side effects from Mounjaro that might cause additional stress To prevent spreading the virus: Avoid kissing or oral sex while lesions are present Don't share items that touch the affected area (lip balm, cutlery, towels) Wash hands thoroughly after touching the cold sore Take special care around newborns, pregnant women and immunocompromised people Continue taking Mounjaro as prescribed unless specifically advised otherwise by your doctor

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