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Aesthetic Surgery Journal, 44 (1), 6067

Canadian Market Considerations Future Developments Frequently Asked Questions Glossary References Understanding Mazdutide and Retatrutide: The Next Generation of Weight Loss Peptides The obesity treatment landscape has transformed dramatically over the past five years

Total weight loss at 48-68 weeks on the combination is difficult to predict without clinical trial data, but based on individual compound data (retatrutide at 24-28.7% and the additive benefit seen with CagriSema), a reasonable estimate for the combination is 25-35% total body weight reduction in high responders

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