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See Full Prescribing Information For Complete Boxed Warning OZEMPIC (semaglutide) is a GLP-1 receptor agonist approved for improving glycemic control in adults with type 2 diabetes, but is contraindicated in patients with a history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

These include: pain radiating down the leg numbness or tingling in the arms or legs pain that worsens when sitting relief when lying down weakness in the arms or legs When these symptoms occur, further evaluation may help determine whether a disc problem is involved

7j and Supplementary Fig