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Some patients report mild insomnia during the first 12 weeks of therapy, but this correlates with overall sympathetic nervous system adjustment to caloric deficit rather than time-of-day injection effects

Noom expands its GLP-1 range with 'microdose' package Digital health company Noom has started offering lower doses of GLP-1 agonist semaglutide, the active ingredient in Novo Nordisk's weight-loss drug Wegovy, at a knock-down price

GLP-1RAs (Glucagon-like peptide 1 receptor agonists) benefit not only blood sugar but obese and related metabolic disorders

Key points Incretins have an important role in glucose homeostasis, regulation of appetite, energy expenditure and immunity