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An imbalance between antioxidants and oxidants directs to the state of oxidative stress, which has the potential to cause damage to biological molecules, including proteins, carbohydrates, lipids, and DNA ( Antioxidants are crucial in fighting oxidative stress as they neutralize or remove free radicals through electron donation ( 4.3 Inflammation Regarding the inflammatory effect of LZD, the present study found that serum IL1- as well as TNF- in LZD-treated rats were significantly elevated compared to non-treated control rats

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The dimer then binds to specific response elements, resulting in transcriptional activation of genes regulating P450 expression (Liang et al