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Importantly, tirzepatide carries a boxed warning for risk of thyroid C-cell tumors and is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or in patients with Multiple Endocrine Neoplasia syndrome type 2

Brand-name drugs are subject to pharmaceutical company pricing, which can be significantly higher due to research, development, and marketing costs and corporate profitability

Proper technique matters: injections into adipose tissue can slow uptake and change effect

On the other hand, surgical removal of the fallopian tubes followed by assisted reproductive measures may be recommended to women with severe tubal disease affecting both tubes