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pCR was assessed at each follow-up visit ( 3, 6, 12, 24 months after diagnosis) using the IDAA1c (Insulin Dose Adjusted A1c) index: HbA1c (%) + [4 x insulin dose (U / kg / d)]

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In a STEP 1 DXA substudy analysis, semaglutide was associated with large fat loss and a smallerbut measurablereduction in total lean body mass over 68 weeks (STEP 1 DXA body composition analysis)