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The results showed that GPX3 silencing only affected G0/G1 checkpoint proteins but not G2/M checkpoint proteins expression

Based on the intra-islet hypothesis, the anatomical correlate of which is that blood within the islets flows from beta cells to alpha cells to delta cells, the local actions of somatostatin would be expected to be negligible [2, 3], while secreted somatostatin would be expected to be exported for extra-islet actions