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Possible Mechanisms of Pain While no direct link between semaglutide and neck pain has been found, researchers propose a few possible explanations for musculoskeletal discomfort in some patients using GLP-1 receptor agonists: Inflammation : In rare cases, medications can trigger low-grade inflammation in the body

doi: 10.1007/s40257-022-00677-0 79

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345 Another triple agonist for these receptors, LY3437943, was found to induce robust reductions in plasma glucose and bodyweight in overweight individuals with T2D, demonstrating that this triple agonist could be a future therapeutic option for T2D treatment