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Mechanism of lipoic acid in the treatment of metabolic dysfunction-associated steatotic liver disease In preclinical studies, LA has been shown to improve nonalcoholic fatty liver disease by modulating a variety of molecular pathways

The irregular sleep-wake rhythm disorder is seen in patients with dementia, which a neurodegenerative process might induce a disruption of the circadian system with a consequent loss of modulatory influence on sleep and wakefulness (104)

Cell Rep (2018) 25(4):92133 e5

In a 24-week trial in 62 overweight or obese women, 28 with PCOS and 34 without, a reduced-calorie, low-glycemic index diet significantly improved acne, menstrual regularity, and testosterone and SHBG levels