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In addition to bile acid metabolites, short-chain fatty acids (SCFAs), primarily composed of acetate (C2), propionate (C3), and butyrate (C4), are beneficial metabolites derived from the fermentation of dietary fiber and resistant starch by the gut microbiota

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Similarly, the in vivo administration of an equimolar dose of DTT (40 mm) instead of NAC to TNBS+ethanol rats failed to either increase GSH levels and protect against injury, suggesting that the beneficial effect of NAC was due to its role as a GSH precursor

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