The IGF-1R promoter exhibits a high basal transcriptional activity, and is under physiological control of nutritional factors (Olchovsky et al, 1993), hormonal stimulation (Clarke et al, 1997) and the developmental stage (Bondy et al, 1992)
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Experimental mice got injections of the peptide 5 times a week, and the results showed that it suppressed the formation of neoplasms, decreased lungs metastases by 1,6 times, multiple tumors by 2 times, 3,7-fold increase of mice without breast tumors and decrease of mice with 6 or more tumors by 3 times
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