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In these studies, at OGTT testing, the persistence of a rise in pulse rate or a rise in haematocrit level at 30 min with treatment was lower than the persistence of hypoglycaemia, suggesting that either this aspect is less reproducible, or that pasireotide is more effective in treating early dumping syndrome (pulse rate rise and haematocrit rise) than in treating late dumping syndrome (hypoglycaemia)

The membrane vacuolar-type H + -ATPase (V-ATPase) is a distinct characteristic of lysosomes and can continuously pump H + into lysosomes to maintain an acidic environment 27