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L-Carnitine can be taken on an empty stomach to potentially improve absorption, but its also fine with food if needed

6) Carnitine is eliminated via urine as free carnitine and acylcarnitines, but more than 95% of carnitine filtered in the kidney is reabsorbed by the proximal tubules therefore maintaining the homeostatic balance of carnitine in the body

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the coa documentation is easy to find too