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For instance, one dietitian noted, The biggest challenge in my opinion on these meds the first two months or six weeks at least appetite is just gone. Another participant who highlighted protein due to its muscle-maintenance role stated, We focus a lot on adequate protein you want to get protein at every eating occasion. The risk of malnutrition, especially when patients experience rapid weight loss, was another concern

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Truong B, Allegri G, Liu XB, Burke KE, Zhu X, Cederbaum SD, Hberle J, Martini PGV, Lipshutz GS (2019) Lipid nanoparticle-targeted mRNA therapy as a treatment for the inherited metabolic liver disorder arginase deficiency