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Green coffees contain about 1% trigonelline, of which 50-80% is degraded upon roasting, and it breaks down to niacin and nicotinic acid and N-methylpyridinium at higher temperatures , as well as volatiles such as pyridine and pyrazines

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LncRNA is associated with various biologically significant processes such as control of chromatin modification, X chromosome silencing, nuclear transport, transcriptional interference, transcriptional activation, genomic imprinting, dosage compensation, and gene expression [139]