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Description

confirmed that DFP effectively reduced nigrostriatal iron burdenevidenced by an increase of 1.8 ms in T2* relaxation time of the right substantia nigra compared to 0.0 ms in the placebo group (standardized difference 0.41, 95% CI 0.100.72)this iron depletion was accompanied by a paradoxical worsening of clinical outcomes

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N Engl J Med 391(2):109121

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