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Chronic gut permeability is where it becomes a problem LPS crossing into the bloodstream can get past the blood-brain barrier too When it does, it activates microglia (the brains immune cells) which start breaking down the blood-brain barrier

For individuals who prefer not to use injections or who may be transitioning off GLP-1 therapy, there are also oral weight loss program options that a provider may consider as part of a broader, medically guided plan

Additionally, the membership includes discounts on GLP-1 medications and other related treatments

A 2024 Swedish study followed 3,249 MS patients for an average of 10.6 years and found that obesity was associated with: 4 43% higher risk of reaching EDSS 3 (moderate disability) 40% higher risk of reaching EDSS 4 (significant walking impairment) More rapid cognitive decline Higher MRI activity showing new brain lesions A German study of 1,066 MS patients found that obese patients reached disability milestones more quickly than those with normal weight