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We informed the public of our findings and the changes that we made in the January 2024 OPPS Update (Transmittal 12421, Change Request 13488), dated December 21, 2023

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Collagen Production and Tissue Regeneration It increases fibroblast activity, the cells responsible for producing collagen and repairing connective tissues such as tendons and ligaments

This was confirmed across multiple studies measuring serum IGF-1 at baseline and throughout treatment