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J Endocrinol Investig 19:433440 Muoz MT, Barrios V, Pozo J, Argente J (1996) Insulin-like growth factor I, its binding proteins 1 and 3, and growth hormone-binding protein in children and adolescents with insulin-dependent diabetes mellitus: clinical implications

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Nevertheless, current GSH-activated prodrugs frequently face challenges in achieving selective activation within heterogeneous tumor microenvironments

Tertiary structure the final 3-D shape of one protein chain Quaternary structure Several polypeptide chains come together to form the functional protein