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Research applications include in vitro aromatase enzyme kinetics and inhibition modelling, estrogen biosynthesis pathway analysis in steroidogenesis cell line models, and comparative aromatase inhibitor studies examining binding potency and selectivity across the triazole class

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For observational studies reporting serum vitamin B12 levels, the certainty of evidence was upgraded from low to moderate due to the large and consistent magnitude of effect across studies, despite heterogeneity