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Whilst NICE has not yet issued specific guidance on retatrutide reflecting its investigational status existing NICE and NHS frameworks for GLP-1 receptor agonists and nutritional deficiency management provide a relevant and applicable foundation for clinical practice

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However, a clinical trial revealed that patients who received lixisenatide showed a lower incidence of hypoglycemia than patients receiving twice-daily exenatide (lixisenatide, 2.5% vs

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