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In this system, O 2 is reduced by cytochrome-c oxidase, which is the terminal enzymatic component of this mitochondrial enzymatic complex

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The PRDX-GSH axis PRDXs constitute a family of cysteine-dependent peroxidases that regulate intracellular H 2 O 2 and lipid peroxide levels 102

To put it another way, Long COVID is associated with immune-inflammatory processes and decreased ANTIOX, while a subgroup of Long COVID patients additionally exhibits increased NO production, oxidative damage to proteins (PCs) and lipids with increased aldehyde formation (MDA), and an immune-oxidative stress response (increased MPO and CRP)