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The RA cases met the 1987 diagnostic criteria of the American College of Rheumatology or the 2010 updated criteria of the American College of Rheumatology/European League Against Rheumatism [14]

CD38 has experimentally been proven to play a role in the regulation of cellular metabolism, inflammation, and oxidative stress 134

gov, "A double-blind, placebo-controlled, randomized INTerventional Clinical Trial (SARA-INT) (SARA-INT)"

Another meta-analysis study of 12 randomized controlled trials involving non-dialysis patients revealed that biotic supplements did not significantly reduce the serum creatinine levels compared to the placebo group (Liu F