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43 KefasB.GodlewskiJ.ComeauL.LiY.AbounaderR.HawkinsonM.et al (2008)

Although approved for up to 12 weeks, some clinicians prescribe it off-label for longer periods

Russo, F

It is essential to verify the patients understanding of the prescribed therapeutic regimen, clarify the benefits that can result from the therapy, discuss possible adverse events, and provide useful advice to minimize them, as well as simplify the therapeutic regimen when appropriate [73]