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Prolonged illness, chronic stress and intensive physical exertion can temporarily lower levels further, as the body then consumes more glutathione than it produces

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For example, one study found that a single dose of oxytocin nasal spray resulted in decreased food intake and reduced impulsivity among overweight men

This is in keeping with the rapid onset of the behavioural signs of nociception7 and rapid changes in the responses of dorsal horn cells 23 following formalin