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e-mail: [email protected] This article was submitted to Frontiers in Ethnopharmacology, a specialty of Frontiers in Pharmacology

In the connection to metabolism, boosting mitochondrial metabolism of LAC rapidly regulates central and peripheral insulin resistance (IR) [67], which is metabolic dysfunction implicated in the pathophysiology of both MDD and AD [68]

Liver disease fatty liver, alcohol-related liver disease, and chronic hepatitis all elevate ferritin Frequent blood transfusions transfusional iron overload Excessive iron supplementation taking iron without confirmed deficiency Why it matters: Untreated iron overload deposits iron in the liver, heart, pancreas, and joints leading to cirrhosis, cardiomyopathy, diabetes, and arthritis

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