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Phielix E, Jelenik T, Nowotny P, et al Reduction of nonesterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial

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These sex-based differences were largely consistent across 12 advanced solid tumour types, as well as treatment modalities, including chemotherapy, targeted therapies and immunotherapy, suggesting they stem from underlying biological mechanisms, not just drug-specific effects, researchers said