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We hypothesised that the reported brainstem transcriptomic changes might reflect modulation of NTS Ppg neuron activity downstream of GIPR antagonism in the hypothalamus and therefore tested the effect of GIPR-antag on mice with ablated NTS Ppg neurons (Ppg NTS-Abl ) generated by bilateral stereotactic injection of AAV-DTA into the NTS of Ppg-Cre or control mice (Cre-negative mice receiving AAV-DTA into the NTS) (Fig

The American Academy of Family Physicians (AAFP) notes that having anywhere from three bowel movements a day to three a week is considered normal

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1 In adults, common symptoms include fever, cough, body aches, lack of smell and taste, dyspnea, and/or fatigue