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Quick Answer: GLP-1 receptor agonists can be safely used in people with high blood pressure and may produce modest reductions in systolic blood pressure of 25 mmHg alongside broader cardiovascular benefits

The addition of the acetyl group also endows acetyl L-carnitine (ALC) with a greater solubility in water, which enables it not only to diffuse easily across the inner wall of the mitochondria and into the cell cytosol, but also cross cell membranes in general more easily

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