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General recovery optimization

Most patients begin to notice gradual weight loss within a few weeks, with more significant results appearing after 3 to 6 months of consistent use

Key among these are GLP-1 receptor agonists and dual GIP/GLP-1 receptor agonists, which not only help lower A1c levels but also promote significant weight loss and potential cardiovascular and neurological benefits

However, as gallbladder disease is not an issue with sodium-glucose co-transporter-2 (SGLT-2) inhibitors (with similar weight loss) (89), and gallbladder events also occurred in GLP-1RA-treated patients well after weight reduction (90), other mechanisms are possibly in play