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Once the mechanism works, the question shifts from who can build it to who controls it, and that's where most teams are underprepared." Across the landscape: Novo Nordisk is building across multiple triple-agonist assets Pfizer has entered through acquisition Hanmi is advancing the only clinical-stage small-molecule triple Innovent, Hengrui, and multiple Chinese sponsors are scaling pipeline depth Sanofi holds the largest IP position without a disclosed asset 27 programs

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