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However, some patients report sleep disturbances that may occur indirectly through gastrointestinal symptoms, blood glucose changes, or metabolic adjustments

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As the dosage increases over time, the appetite-suppressing effects often become stronger and more consistent, helping patients develop healthier eating habits and steady progress toward their weight-loss goals

The conclusive proof: the effect is abolished in animals CD36 knockout closest preserved in animals GHS-R1a knockout This means that the cardioprotective effect is mediated exclusively by CD36, not by the classical GH axis