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Extended continuous use can reduce receptor sensitivity and potentially cause copper accumulation concerns

Although normal therapeutic doses of this product ordinarily deliver amounts of benzyl alcohol that are substantially lower than those reported in association with the gasping syndrome, the minimum amount of benzyl alcohol at which toxicity may occur is not known

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DID analysis further supports these trends, showing a marginally significant increase in walking frequency (0.41 days per week, p=0.070) but statistically insignificant changes in walking duration and overall PA scores