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Description

Glucagon-like peptide-1 induces cell proliferation and pancreatic-duodenum homeobox-1 expression and increases endocrine cell mass in the pancreas of old, glucose-intolerant rats

The nausea at higher doses without adequate adaptation can be severe enough to force protocol abandonment entirely

S2CID 206357650

On the other hand, the fact that the mean HbA1c level in our subjects (5.8%) is near normal values could also hamper the finding of a more meaningful effect