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4,5,6 Since 2008, the Food and Drug Administration (FDA) and European Medicines Agency have required that new T2D pharmacotherapies undergo rigorous cardiovascular safety clinical trials using hard cardiovascular endpoints and more stringent statistical review

Thus, GLP-1-based therapy is nowadays widely used in the treatment of type 2 diabetes, especially in obese subjects

People with autoimmune conditions like Hashimoto thyroiditis or endometriosis should discuss the combination with their specialist

Generally safe options include acetaminophen, ibuprofen/naproxen (with food), guaifenesin, saline nasal sprays, sugar-free throat lozenges, and antihistamines