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doi: 10.1007/164_2020_388 121 WatanabeSMoniagaCSNielsenSHara-ChikumaM

The proportion of lean mass loss to fat mass loss has generally been recommended that 25% of the lost weight should be fat free mass the Quarter FFM Rule. [26] Before the advent of these newer medications, excessive loss of fat free mass, and particularly muscle mass, has not been a clinical issue