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The reporter of Cas12f with sgRNA for TTR was also constructed under the CMV promotor of pKLV2 vector, which has mCherry followed by T2A and TTR target sequence, further followed by the frameshifted two GFP sequences, IRES, and hygromycin resistance gene, resulting in pKLV2mCherry_TTR_GFPGFPv3
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Because only one study focused on lithium, we conducted a sensitivity analysis to include only studies of N -acetylcysteine, using meta-regression to evaluate the following potential confounding factors: (1) mean age (years), (2) diagnosis (OCD or OCD-related disorders), (3) study duration (in weeks), (4) total number of individuals, and (5) percentage of female participants
