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Inflammatory Microenvironment Research Both peptides are theorized to support the inflammatory milieu: BPC157 is believed to modulate cytokine signaling to support controlled inflammation and repair, while TB500 seems to reduce chronic inflammatory signaling and support tissue pliability

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In 2018, Amazentis SA received a favorable Generally Recognized As Safe (GRAS) review of Mitopure from the FDA

This specific sequence was engineered based on the observation that alternating cationic and aromatic residues have a strong affinity for cardiolipin a phospholipid found almost exclusively on the inner mitochondrial membrane