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it means the dose-response, long-term safety, and population-level risk profile of Melanotan II in humans are fundamentally unknown

[DOI] [PMC free article] [PubMed] [Google Scholar] 18.Aronne LJ, Sattar N, Horn DB, et al

In the MISER trial reported by Bang et al., 26 of 32 surgical patients (81.3%) underwent cystogastrostomy, while three patients were converted to endoscopic management because of intraoperative cardiovascular instability or technical failure